Uremic Solutes Database
Solute Details for Retinol Binding Protein (RBP)
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Base data
Name Retinol Binding Protein (RBP)
Molecular weight 21200
Group Protein
Class Protein-bound
Added 16.09.2009
Reference Pubmed: 12675874
Submitted by Vanholder
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
02.12.200220.70 (+/-4.53) mg/L16Vitamin A, retinol binding protein an...Abou DeifArgiles[15]
Grand mean20.70 (+/-4.53) mg/L16

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
27.10.1994192.00 (+/-78.00) (?-369.20) mg/L112Determinants of the serum concentrati...VanholderAbou Deif
06.04.2013206.90 (+/-20.50) mg/L18The use of SDS-PAGE scanning of spent...Abou DeifArgiles
Grand mean194.06 (+/-72.80) (192.00-369.20) mg/L130
ANOVAF(1,128) = 0.09, p=0.76: No significant differences between group means.
DispersionL:192.00, M:194.06, H:369.20 : A - (Minimal scatter: High consistency.)

Relative increase (CU/CN) 9.38 times higher than the average normal concentration.

Pathological associations
11.08.2004ImmunologicRetinol binding protein isolated from...The apo- and holo-forms of RBP inhibit chemotaxis, oxidative metabolism and apoptosis. RBP may be considered a uraemic toxin, contributing to a disturbed immune defence.

15Standard error converted to standard deviation as SD = SEM * sqrt(n)